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Application note

On-line crystallization monitoring: Slurry Flow Cell for in situ investigation of crystallization processes

This application note describes the use of a PreFIX Slurry Flow Cell for research-scale crystallization experiments on a PANalytical X-ray diffractometer. Transmission experiments were performed to monitor and analyze crystallization processes from the very first stages up to high crystallite concentrations.

The basics of crystallization, such as the fundamentals of thermodynamics, kinetics, and structure, are well established. However, the application of these basics to solve crystallization process problems is complicated with a large number of tools for the practicing scientist or engineer to make use of.

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